Numerous American Airlines aircraft at Dallas/Fort Worth International Airport in 2005
In early July 2010, it was reported that American Airlines was trying to find buyers for its regional airline American Eagle. The move followed Delta Air Lines and its spin off of its wholly owned regional airlines Compass Airlines and Mesaba Airlines.
American began a joint venture with British Airways and Iberia Airlines in October 2010, which included frequent flyer reciprocity. The USDOT granted AA preliminary antitrust immunity for the venture in February 2010, and the partnership was officially approved by the USDOT on July 20, 2010.
American also announced an interlining partnership with JetBlue Airways in March 2010, which covered 27 JetBlue destinations not served by American and 13 American international destinations from New York and Boston. American gave JetBlue eight slot pairs (arrival and departure slots) at Ronald Reagan Washington National Airport and one slot pair at Westchester County Airport, in return for which JetBlue gave American 12 slot pairs at JFK Airport. Effective November 18, 2010, the two airlines would give travelers miles in either airline's frequent flyer program when flying on a qualifying route, regardless of whether the travels include an international connection.
American expanded its service to Asia. It was one of the initial US bidders in February 2010 to serve Tokyo's Haneda Airport, and was awarded rights to serve Haneda from New York JFK. American planned to begin JFK-Haneda service in January 2011, but postponed the service until February 2011 citing low booking demand, ultimately terminating its JFK-Narita service in favor of JFK-Haneda service in June 2012. American also began service between Los Angeles and Shanghai in 2011 and between Dallas/Fort Worth and Seoul in 2013, and announced the launch of service from Dallas/Fort Worth International Airport to both Shanghai and Hong Kong in the summer of 2014, providing the first ever nonstop service between Dallas/Fort Worth and China.
Since late 2010, American Airlines has been involved in a dispute with two online ticketing agencies, Expedia and Orbitz. This relates to American's "Direct Connect" fare booking system for large travel agents, which Expedia claimed might raise costs and was less transparent for passengers. The Direct Connect allows American to exert more control over its distribution, save costs, and better sell ancillary services to its customers. In December 2010, American pulled its price listings from Orbitz, and on January 1, 2011, Expedia removed American Airlines' fares from its site.
American placed the "largest aircraft order in history" in July 2011, purchasing 460 "next generation" Boeing 737 and Airbus A320 aircraft for delivery between 2013 and 2022. These aircraft were designated to replace American's short and medium-haul fleet of 757-200, 767-200, and MD-80 aircraft, eventually consolidating the fleet around four aircraft families (Boeing 737, Airbus A320, Boeing 787, and Boeing 777).